 Following
an ionizing circular polarized laser pulse that crosses a sample, ions and
electrons are extracted in opposing directions to their respective detectors. The
complete momentum of electrons is obtained from a time- and position-sensitive
imaging detector. Mass analysis is achieved by measuring the ion Time-of-Flight.
Coincidence detection of a mass-selected ion and an electron identifies
particles from a single molecular ionization event. The mass-tagged
electron distribution displays a forward-backward angular asymmetry (PECD) along
the laser beam that can distinguish between enantiomers (S-M versus R-M), while
the radius of the distribution maps the electron kinetic energy. The asymmetry
reveals that the compound is chiral. Start of theoretical concept development and calculations 1976 Publication by Ritchie on the theoretical concept of PhotoElectron Circular Dichroism 1982 Publication by Cherepkov on the quantum theory of photoelectron angular distribution from a chiral molecule 2000 Publication by Powis of the first theoretical calculation of the magnitude of PECD in a real molecule Start of experimental synchrotron-based single photon PECD (2001-2015) 2001 Publication by Heinzmann and coworkers of the first experimental verification of PECD asymmetry obtained with synchrotron radiation 2003 Publication by Powis, Nahon and coworkers of the first full electron angular distribution of PECD obtained with synchrotron radiation 2015 Publication by Mairesse and coworkers on HHG-based single photon PECD Start of experimental table-top laser-based multiphoton MS-PECD (2008-2015) 2008 Publication by Janssen, Vredenborg and coworkers on a novel laser-based electron-ion coincidence imaging spectrometer 2008 First email discussion by Janssen and Powis on the potential and merits of laser-based multiphoton PECD 2010 EU-proposal submitted by Janssen and coworkers to study chiral molecules with polarization shaped laser and coincidence imaging 2011 Publication by Janssen, Vredenborg and coworkers on our proposition for direct MS of chiral molecules by laser-based MS-PECD 2011 First paper on multiphoton MS-PECD by Janssen and coworkers submitted to and rejected by Nature 2011 Lecture by Janssen at CFEL/DESY in Hamburg on first experimental results of laser-based multi-photon MS-PECD in camphor 2011 Proposal by Janssen to the Netherlands Organisation for Scientific Research for further science and development of MS-PECD 2012 Submission by Janssen of first experimental results of laser-based MS-PECD at Ultrafast Phenomena Conference Lausanne 2012 2012 Publication by Janssen and coworkers of first results of laser-based MS-PECD published at Ultrafast Phenomena Conference, July 2012 2012 Publication by Baumert and coworkers on non-mass selected laser-based PECD 2013 Publication by Janssen, Powis and coworkers of full experimental results, data analysis and theoretical modelling of MS-PECD (J. Chem. Phys. Editor Award for groundbreaking research in Chemical Physics) 2014 Invited Perspective by Janssen and Powis on science, technology and applications of synchrotron-based and laser-based MS-PECD 2014 Lecture at Chirality 2014 Conference Prague of first experimental results of laser-based MS-PECD in multi-component mixture 2015 Publication by Janssen, Powis and coworkers in Nature Communications on enantiomeric excess measurements in multi-component mixtures by MS-PECD 2015 Janssen founds company MassSpecpecD BV and receives The Analytical Scientist Innovation Award 2015 Recent citations to review papers on laser-based and synchrotron-based PECD: Review on Laser-based PECD by Janssen and Powis, PhysChemChemPhys 2014: Google Scholar citations Review on Synchrotron-based PECD by Nahon, Garcia and Powis, J. of Elec. Spec. & Rel. Phen.: Google Scholar citations This website is designed and operated by MassSpecpecD BV, the Netherlands. |
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